dc.contributor.author | Croft, J | |
dc.contributor.author | Riddell, A | |
dc.contributor.author | Koh, D-M | |
dc.contributor.author | Downey, K | |
dc.contributor.author | Blackledge, M | |
dc.contributor.author | Usher, M | |
dc.contributor.author | Boyd, K | |
dc.contributor.author | Kaiser, M | |
dc.contributor.author | Messiou, C | |
dc.date.accessioned | 2020-08-12T11:24:09Z | |
dc.date.issued | 2020-07-14 | |
dc.identifier.citation | Cancer imaging : the official publication of the International Cancer Imaging Society, 2020, 20 (1), pp. 48 - ? | |
dc.identifier.issn | 1740-5025 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/3935 | |
dc.identifier.eissn | 1470-7330 | |
dc.identifier.doi | 10.1186/s40644-020-00328-9 | |
dc.description.abstract | BACKGROUND: Whole body magnetic resonance imaging (MRI) is now incorporated into international guidance for imaging patients with multiple myeloma. The aim of this study was to investigate inter-observer agreement of triple reported baseline whole-body MRI in myeloma and highlight potential pitfalls. METHODS: Fifty-seven patients with symptomatic myeloma at first presentation or relapse and planned for autologous stem cell transplant were included. All patients completed baseline whole body MRI within 2 weeks prior to starting treatment. Each scan was reported independently by 3 radiologists using a defined scoring system. Differences in observer scores were compared using analysis of variance (ANOVA) and inter-observer agreement assessed using intra class correlation coefficient (ICC). RESULTS: There was no significant difference in mean observer scores for whole skeleton and ICC demonstrated excellent inter-observer agreement at 0.91. ICC varied between skeletal regions with spine, pelvis and ribs showing good inter-observer agreement, whereas skull and long bones were moderate. Scans with variation in observer scores were re-examined and cause of discrepancies identified. This information was used to describe potential anatomical pitfalls in reporting . CONCLUSION: Whole-body MRI has excellent inter-observer agreement in reporting symptomatic myeloma at baseline. Inter-observer agreement varied between skeletal regions highlighting specific areas of difficulty. | |
dc.format | Electronic | |
dc.format.extent | 48 - ? | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | BMC | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
dc.subject | Humans | |
dc.subject | Multiple Myeloma | |
dc.subject | Observer Variation | |
dc.subject | Magnetic Resonance Imaging | |
dc.subject | Reproducibility of Results | |
dc.subject | Middle Aged | |
dc.subject | Female | |
dc.subject | Male | |
dc.subject | Whole Body Imaging | |
dc.title | Inter-observer agreement of baseline whole body MRI in multiple myeloma. | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2020-07-08 | |
rioxxterms.versionofrecord | 10.1186/s40644-020-00328-9 | |
rioxxterms.licenseref.uri | https://creativecommons.org/licenses/by/4.0 | |
rioxxterms.licenseref.startdate | 2020-07-14 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | Cancer imaging : the official publication of the International Cancer Imaging Society | |
pubs.issue | 1 | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Molecular Pathology | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Molecular Pathology/Myeloma Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Computational Imaging | |
pubs.organisational-group | /ICR/Primary Group/Royal Marsden Clinical Units | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Molecular Pathology | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Molecular Pathology/Myeloma Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Computational Imaging | |
pubs.organisational-group | /ICR/Primary Group/Royal Marsden Clinical Units | |
pubs.publication-status | Published | |
pubs.volume | 20 | |
pubs.embargo.terms | Not known | |
icr.researchteam | Myeloma Group | |
icr.researchteam | Computational Imaging | |
dc.contributor.icrauthor | Croft, James | |
dc.contributor.icrauthor | Blackledge, Matthew | |
dc.contributor.icrauthor | Kaiser, Martin | |