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dc.contributor.authorCroft, J
dc.contributor.authorRiddell, A
dc.contributor.authorKoh, D-M
dc.contributor.authorDowney, K
dc.contributor.authorBlackledge, M
dc.contributor.authorUsher, M
dc.contributor.authorBoyd, K
dc.contributor.authorKaiser, M
dc.contributor.authorMessiou, C
dc.date.accessioned2020-08-12T11:24:09Z
dc.date.issued2020-07-14
dc.identifier.citationCancer imaging : the official publication of the International Cancer Imaging Society, 2020, 20 (1), pp. 48 - ?
dc.identifier.issn1740-5025
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3935
dc.identifier.eissn1470-7330
dc.identifier.doi10.1186/s40644-020-00328-9
dc.description.abstractBackground Whole body magnetic resonance imaging (MRI) is now incorporated into international guidance for imaging patients with multiple myeloma. The aim of this study was to investigate inter-observer agreement of triple reported baseline whole-body MRI in myeloma and highlight potential pitfalls.Methods Fifty-seven patients with symptomatic myeloma at first presentation or relapse and planned for autologous stem cell transplant were included. All patients completed baseline whole body MRI within 2 weeks prior to starting treatment. Each scan was reported independently by 3 radiologists using a defined scoring system. Differences in observer scores were compared using analysis of variance (ANOVA) and inter-observer agreement assessed using intra class correlation coefficient (ICC).Results There was no significant difference in mean observer scores for whole skeleton and ICC demonstrated excellent inter-observer agreement at 0.91. ICC varied between skeletal regions with spine, pelvis and ribs showing good inter-observer agreement, whereas skull and long bones were moderate. Scans with variation in observer scores were re-examined and cause of discrepancies identified. This information was used to describe potential anatomical pitfalls in reporting .Conclusion Whole-body MRI has excellent inter-observer agreement in reporting symptomatic myeloma at baseline. Inter-observer agreement varied between skeletal regions highlighting specific areas of difficulty.
dc.formatElectronic
dc.format.extent48 - ?
dc.languageeng
dc.language.isoeng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectHumans
dc.subjectMultiple Myeloma
dc.subjectObserver Variation
dc.subjectMagnetic Resonance Imaging
dc.subjectReproducibility of Results
dc.subjectMiddle Aged
dc.subjectFemale
dc.subjectMale
dc.subjectWhole Body Imaging
dc.titleInter-observer agreement of baseline whole body MRI in multiple myeloma.
dc.typeJournal Article
dcterms.dateAccepted2020-07-08
rioxxterms.versionofrecord10.1186/s40644-020-00328-9
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2020-07-14
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfCancer imaging : the official publication of the International Cancer Imaging Society
pubs.issue1
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology/Myeloma Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Computational Imaging
pubs.organisational-group/ICR/Primary Group/Royal Marsden Clinical Units
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology/Myeloma Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Computational Imaging
pubs.organisational-group/ICR/Primary Group/Royal Marsden Clinical Units
pubs.publication-statusPublished
pubs.volume20en_US
pubs.embargo.termsNot known
icr.researchteamMyeloma Groupen_US
icr.researchteamComputational Imagingen_US
dc.contributor.icrauthorKaiser, Martinen
dc.contributor.icrauthorMessiou, Christinaen
dc.contributor.icrauthorBlackledge, Matthewen
dc.contributor.icrauthorKoh, Dow-Muen


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