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COMPOUNDS AND THEIR USES

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Publication Date
2013-02-21
ICR Author
Newton, Gary
Lord, Christopher
Author
Newton, G
Lord, C
Type
Patent
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Abstract
The invention provides a compound that is an inhibitor of one or both of TBK1 and IKKe, or a down-regulator of the expression of one or both of TBK1 and IKKe, for use in a method of treating a cancer that is dependent on the PI3kinase pathway. The invention further provides a method of treating cancer in an individual in whom the cancer is dependent on the PI3kinase pathway, comprising administering to the individual a compound that is an inhibitor of one or both of TBK1 and IKKe, or a down-regulator of the expression of one or both of TBK1 and IKKe.
URL
https://repository.icr.ac.uk/handle/internal/3990
Collections
  • Breast Cancer Research
  • Cancer Therapeutics
  • Molecular Pathology
Subject
Kinase
Oncology
Research team
Medicinal Chemistry 3
Gene Function
License start date
2013-02-21
Citation
2013

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