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dc.contributor.authorLowe, MEen_US
dc.contributor.authorAndersen, DKen_US
dc.contributor.authorCaprioli, RMen_US
dc.contributor.authorChoudhary, Jen_US
dc.contributor.authorCruz-Monserrate, Zen_US
dc.contributor.authorDasyam, AKen_US
dc.contributor.authorForsmark, CEen_US
dc.contributor.authorGorelick, FSen_US
dc.contributor.authorGray, JWen_US
dc.contributor.authorHaupt, Men_US
dc.contributor.authorKelly, KAen_US
dc.contributor.authorOlive, KPen_US
dc.contributor.authorPlevritis, SKen_US
dc.contributor.authorRappaport, Nen_US
dc.contributor.authorRoth, HRen_US
dc.contributor.authorSteen, Hen_US
dc.contributor.authorSwamidass, SJen_US
dc.contributor.authorTirkes, Ten_US
dc.contributor.authorUc, Aen_US
dc.contributor.authorVeselkov, Ken_US
dc.contributor.authorWhitcomb, DCen_US
dc.contributor.authorHabtezion, Aen_US
dc.date.accessioned2020-10-16T09:46:20Z
dc.date.issued2019-11en_US
dc.identifier.citationPancreas, 2019, 48 (10), pp. 1250 - 1258en_US
dc.identifier.issn0885-3177en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/4175
dc.identifier.eissn1536-4828en_US
dc.identifier.doi10.1097/mpa.0000000000001412en_US
dc.description.abstractA workshop on research gaps and opportunities for Precision Medicine in Pancreatic Disease was sponsored by the National Institute of Diabetes and Digestive Kidney Diseases on July 24, 2019, in Pittsburgh. The workshop included an overview lecture on precision medicine in cancer and 4 sessions: (1) general considerations for the application of bioinformatics and artificial intelligence; (2) omics, the combination of risk factors and biomarkers; (3) precision imaging; and (4) gaps, barriers, and needs to move from precision to personalized medicine for pancreatic disease. Current precision medicine approaches and tools were reviewed, and participants identified knowledge gaps and research needs that hinder bringing precision medicine to pancreatic diseases. Most critical were (a) multicenter efforts to collect large-scale patient data sets from multiple data streams in the context of environmental and social factors; (b) new information systems that can collect, annotate, and quantify data to inform disease mechanisms; (c) novel prospective clinical trial designs to test and improve therapies; and (d) a framework for measuring and assessing the value of proposed approaches to the health care system. With these advances, precision medicine can identify patients early in the course of their pancreatic disease and prevent progression to chronic or fatal illness.en_US
dc.formatPrinten_US
dc.format.extent1250 - 1258en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://www.rioxx.net/licenses/all-rights-reserveden_US
dc.subjectHumansen_US
dc.subjectPancreatic Diseasesen_US
dc.subjectComputational Biologyen_US
dc.subjectResearchen_US
dc.subjectBiomedical Researchen_US
dc.subjectMetabolomicsen_US
dc.subjectDatasets as Topicen_US
dc.subjectBiomarkersen_US
dc.subjectPrecision Medicineen_US
dc.subjectDeep Learningen_US
dc.titlePrecision Medicine in Pancreatic Disease-Knowledge Gaps and Research Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.en_US
dc.typeJournal Article
dcterms.dateAccepted2019-11-09en_US
rioxxterms.versionofrecord10.1097/mpa.0000000000001412en_US
rioxxterms.licenseref.startdate2019-11en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfPancreasen_US
pubs.issue10en_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.publication-statusPublisheden_US
pubs.volume48en_US
pubs.embargo.termsNot knownen_US
dc.contributor.icrauthorChoudhary, Jyotien_US


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