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dc.contributor.authorDouzinas, EE
dc.contributor.authorAndrianakis, I
dc.contributor.authorLivaditi, O
dc.contributor.authorBakos, D
dc.contributor.authorFlevari, K
dc.contributor.authorGoutas, N
dc.contributor.authorVlachodimitropoulos, D
dc.contributor.authorTasoulis, M-K
dc.contributor.authorBetrosian, AP
dc.date.accessioned2022-05-16T14:58:37Z
dc.date.available2022-05-16T14:58:37Z
dc.identifier.citationWorld journal of gastroenterology, 2009, 15 (43), pp. 5455 - 5460en
dc.identifier.issn1007-9327
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/5128
dc.identifier.eissn2219-2840en_US
dc.identifier.eissn2219-2840
dc.identifier.doi10.3748/wjg.15.5455en_US
dc.identifier.doi10.3748/wjg.15.5455
dc.description.abstract<h4>Aim</h4>To investigate factors predicting failure of percutaneous endoscopic gastrostomy (PEG) to eliminate gastroesophageal reflux (GER).<h4>Methods</h4>Twenty-nine consecutive mechanically ventilated patients were investigated. Patients were evaluated for GER by pH-metry pre-PEG and on the 7th post-PEG day. Endoscopic and histologic evidence of reflux esophagitis was also carried out. A beneficial response to PEG was considered when pH-metry on the 7th post-PEG day showed that GER was below 4%.<h4>Results</h4>Seventeen patients responded (RESP group) and 12 did not respond (N-RESP) to PEG. The mean age, sex, weight and APACHE II score were similar in both groups. GER (%) values were similar in both groups at baseline, but were significantly reduced in the RESP group compared with the N-RESP group on the 7th post-PEG day [2.5 (0.6-3.8) vs 8.1 (7.4-9.2, P < 0.001)]. Reflux esophagitis and the gastroesophageal flap valve (GEFV) grading differed significantly between the two groups (P = 0.031 and P = 0.020, respectively). Histology revealed no significant differences between the two groups.<h4>Conclusion</h4>Endoscopic grading of GEFV and the presence of severe reflux esophagitis are predisposing factors for failure of PEG to reduce GER in mechanically ventilated patients.en_US
dc.formatPrinten_US
dc.format.extent5455 - 5460en_US
dc.languageengen_US
dc.language.isoengen
dc.rights.urihttp://www.rioxx.net/licenses/all-rights-reserveden
dc.subjectHumansen_US
dc.subjectGastroesophageal Refluxen_US
dc.subjectEsophagitis, Pepticen_US
dc.subjectGastroscopyen_US
dc.subjectEsophagoscopyen_US
dc.subjectEndoscopyen_US
dc.subjectTreatment Outcomeen_US
dc.subjectRespiration, Artificialen_US
dc.subjectEnteral Nutritionen_US
dc.subjectGastrostomyen_US
dc.subjectHydrogen-Ion Concentrationen_US
dc.subjectAdulten_US
dc.subjectAgeden_US
dc.subjectMiddle Ageden_US
dc.subjectFemaleen_US
dc.subjectMaleen_US
dc.titleReasons of PEG failure to eliminate gastroesophageal reflux in mechanically ventilated patients.en
dc.typeJournal Article
dcterms.dateAccepted2009-11-01
rioxxterms.versionVoRen
rioxxterms.versionofrecord10.3748/wjg.15.5455en
dc.relation.isPartOfWorld journal of gastroenterologyen_US
pubs.issue43en_US
pubs.notesNo embargoen_US
pubs.organisational-group/ICR
pubs.publication-statusPublisheden_US
pubs.volume15en_US
pubs.embargo.termsNo embargoen_US
dc.contributor.icrauthorTasoulis, Mariosen_US


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