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Arresting metastasis within the microcirculation.

dc.contributor.authorVarotsos Vrynas, A
dc.contributor.authorPerea Paizal, J
dc.contributor.authorBakal, C
dc.contributor.authorAu, SH
dc.coverage.spatialNetherlands
dc.date.accessioned2022-09-13T09:19:57Z
dc.date.available2022-09-13T09:19:57Z
dc.date.issued2021-07-09
dc.identifier10.1007/s10585-021-10109-8
dc.identifier.citationClinical and Experimental Metastasis, 2021, 38 (4), pp. 337 - 342
dc.identifier.issn0262-0898
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/5447
dc.identifier.eissn1573-7276
dc.identifier.doi10.1007/s10585-021-10109-8
dc.description.abstractThe behaviour of circulating tumour cells in the microcirculation remains poorly understood. Growing evidence suggests that biomechanical adaptations and interactions with blood components, i.e. immune cells and platelets within capillary beds, may add more complexity to CTCs journey towards metastasis. Revisiting how these mediators impact the ability of circulating tumour cells to survive and metastasise, will be vital to understand the role of microcirculation and advance our knowledge on metastasis.
dc.formatPrint-Electronic
dc.format.extent337 - 342
dc.languageeng
dc.language.isoeng
dc.publisherSPRINGER
dc.relation.ispartofClinical and Experimental Metastasis
dc.subjectBiomechanics
dc.subjectCancer
dc.subjectCirculating tumour cells
dc.subjectImmune cells
dc.subjectMetastasis
dc.subjectMicrovasculature
dc.subjectPlatelets
dc.subjectBiomechanical Phenomena
dc.subjectHumans
dc.subjectMicrocirculation
dc.subjectNeoplasm Metastasis
dc.subjectNeoplastic Cells, Circulating
dc.subjectNeutrophils
dc.titleArresting metastasis within the microcirculation.
dc.typeJournal Article
dcterms.dateAccepted2021-06-02
dc.date.updated2022-09-13T09:19:22Z
rioxxterms.versionofrecord10.1007/s10585-021-10109-8
rioxxterms.licenseref.startdate2021-07-09
rioxxterms.typeJournal Article/Review
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/34241735
pubs.issue4
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Biology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Biology/Dynamical Cell Systems
pubs.publication-statusPublished
pubs.publisher-urlhttp://dx.doi.org/10.1007/s10585-021-10109-8
pubs.volume38
icr.researchteamDynamical Cell Systems
dc.contributor.icrauthorBakal, Christopher
icr.provenanceDeposited by Mr Arek Surman on 2022-09-13. Deposit type is initial. No. of files: 1. Files: Arresting metastasis within the microcirculation.pdf


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