Arresting metastasis within the microcirculation.
Date
2021-07-09ICR Author
Author
Varotsos Vrynas, A
Perea Paizal, J
Bakal, C
Au, SH
Type
Journal Article
Metadata
Show full item recordAbstract
The behaviour of circulating tumour cells in the microcirculation remains poorly understood. Growing evidence suggests that biomechanical adaptations and interactions with blood components, i.e. immune cells and platelets within capillary beds, may add more complexity to CTCs journey towards metastasis. Revisiting how these mediators impact the ability of circulating tumour cells to survive and metastasise, will be vital to understand the role of microcirculation and advance our knowledge on metastasis.
Collections
Subject
Biomechanics
Cancer
Circulating tumour cells
Immune cells
Metastasis
Microvasculature
Platelets
Biomechanical Phenomena
Humans
Microcirculation
Neoplasm Metastasis
Neoplastic Cells, Circulating
Neutrophils
Research team
Dynamical Cell Systems
Language
eng
Date accepted
2021-06-02
License start date
2021-07-09
Citation
Clinical and Experimental Metastasis, 2021, 38 (4), pp. 337 - 342
Publisher
SPRINGER