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PEARLS - A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA-avid pelvic and/or para-aortic lymph nodes at presentation.

dc.contributor.authorMurray, J
dc.contributor.authorCruickshank, C
dc.contributor.authorBird, T
dc.contributor.authorBell, P
dc.contributor.authorBraun, J
dc.contributor.authorChuter, D
dc.contributor.authorFerreira, MR
dc.contributor.authorGriffin, C
dc.contributor.authorHassan, S
dc.contributor.authorHujairi, N
dc.contributor.authorMelcher, A
dc.contributor.authorMiles, E
dc.contributor.authorNaismith, O
dc.contributor.authorPanades, M
dc.contributor.authorPhilipps, L
dc.contributor.authorReid, A
dc.contributor.authorRekowski, J
dc.contributor.authorSankey, P
dc.contributor.authorStaffurth, J
dc.contributor.authorSyndikus, I
dc.contributor.authorTree, A
dc.contributor.authorWilkins, A
dc.contributor.authorHall, E
dc.contributor.authorPEARLS Trial Management Group,
dc.coverage.spatialIreland
dc.date.accessioned2022-11-25T09:47:52Z
dc.date.available2022-11-25T09:47:52Z
dc.date.issued2022-11-01
dc.identifierS2405-6308(22)00078-7
dc.identifier.citationClinical and Translational Radiation Oncology, 2022, 37 pp. 130 - 136
dc.identifier.issn2405-6308
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/5576
dc.identifier.eissn2405-6308
dc.identifier.eissn2405-6308
dc.identifier.doi10.1016/j.ctro.2022.09.003
dc.description.abstractPEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral interspace) can improve outcomes for this patient group.
dc.formatElectronic-eCollection
dc.format.extent130 - 136
dc.languageeng
dc.language.isoeng
dc.publisherELSEVIER IRELAND LTD
dc.relation.ispartofClinical and Translational Radiation Oncology
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectIMRT
dc.subjectPSMA-PET
dc.subjectPara-aortic lymph nodes
dc.subjectProstate
dc.subjectRandomized controlled trial
dc.titlePEARLS - A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA-avid pelvic and/or para-aortic lymph nodes at presentation.
dc.typeJournal Article
dcterms.dateAccepted2022-09-18
dc.date.updated2022-11-24T14:40:38Z
rioxxterms.versionVoR
rioxxterms.versionofrecord10.1016/j.ctro.2022.09.003
rioxxterms.licenseref.startdate2022-11-01
rioxxterms.typeJournal Article/Review
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/36238579
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Biology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Biology/Targeted Therapy
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Clinical Trials & Statistics Unit
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Targeted Therapy
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/Clinical Academic Radiotherapy (Dearnaley)
pubs.organisational-group/ICR/Students
pubs.organisational-group/ICR/Students/PhD and MPhil
pubs.organisational-group/ICR/Students/PhD and MPhil/19/20 Starting Cohort
pubs.organisational-group/ICR/ImmNet
pubs.organisational-group/ICR/Students/PhD and MPhil/13/14 Starting Cohort
pubs.publication-statusPublished online
pubs.publisher-urlhttp://dx.doi.org/10.1016/j.ctro.2022.09.003
pubs.volume37
icr.researchteamClinic Acad RT Dearnaley
icr.researchteamClin Trials & Stats Unit
icr.researchteamTargeted Therapy
dc.contributor.icrauthorMurray, Julia
dc.contributor.icrauthorCruickshank, Clare
dc.contributor.icrauthorGriffin, Clare
dc.contributor.icrauthorMelcher, Alan
dc.contributor.icrauthorPhilipps, Lara
dc.contributor.icrauthorCorbett, Anna
dc.contributor.icrauthorHall, Emma
icr.provenanceDeposited by Mrs Jessica Perry (impersonating Prof Emma Hall) on 2022-11-24. Deposit type is initial. No. of files: 1. Files: PEARLS - A multicentre phase IIIII trial of extended field radiotherapy for androgen sensitive prostate cancer patients with.pdf


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