PEARLS - A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA-avid pelvic and/or para-aortic lymph nodes at presentation.
Date
2022-11-01ICR Author
Author
Murray, J
Cruickshank, C
Bird, T
Bell, P
Braun, J
Chuter, D
Ferreira, MR
Griffin, C
Hassan, S
Hujairi, N
Melcher, A
Miles, E
Naismith, O
Panades, M
Philipps, L
Reid, A
Rekowski, J
Sankey, P
Staffurth, J
Syndikus, I
Tree, A
Wilkins, A
Hall, E
PEARLS Trial Management Group,
Type
Journal Article
Metadata
Show full item recordAbstract
PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral interspace) can improve outcomes for this patient group.
Collections
Subject
IMRT
PSMA-PET
Para-aortic lymph nodes
Prostate
Randomized controlled trial
Research team
Clinic Acad RT Dearnaley
Clin Trials & Stats Unit
Targeted Therapy
Language
eng
Date accepted
2022-09-18
License start date
2022-11-01
Citation
Clinical and Translational Radiation Oncology, 2022, 37 pp. 130 - 136
Publisher
ELSEVIER IRELAND LTD