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Synthesis and pre-clinical evaluation of a [F-18] fluoromethyl-tanaproget derivative for imaging of progesterone receptor expression

dc.contributor.authorMerchant, S
dc.contributor.authorAllott, L
dc.contributor.authorCarroll, L
dc.contributor.authorTittrea, V
dc.contributor.authorKealey, S
dc.contributor.authorWitney, TH
dc.contributor.authorMiller, PW
dc.contributor.authorSmith, G
dc.contributor.authorAboagye, EO
dc.date.accessioned2016-08-17T11:19:24Z
dc.date.issued2016-01-01
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000378755200108&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4b848928d1c3e5c86d298abb68475f9
dc.identifier.citationRSC ADVANCES, 2016, 6 (62), pp. S7569 - S7579 (11)
dc.identifier.issn2046-2069
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/55
dc.identifier.doi10.1039/c6ra07404a
dc.description.abstract<p>This work features the synthesis and biological evaluation of a novel fluorinated derivative of tanaproget and a carbon-11 labelled analogue, a high affinity non-steroidal PR ligand, as a possible candidate for imaging PR expression<italic>in vivo</italic>.</p>
dc.format.extentS7569 - S7579 (11)
dc.languageeng
dc.language.isoeng
dc.publisherROYAL SOC CHEMISTRY
dc.subjectScience & Technology
dc.subjectPhysical Sciences
dc.subjectChemistry, Multidisciplinary
dc.subjectChemistry
dc.subjectBREAST-CANCER
dc.subjectENDOCRINE THERAPY
dc.subjectESTROGEN
dc.subjectPET
dc.subjectCARCINOMA
dc.subjectAFFINITY
dc.subjectANALOGS
dc.subjectLIGAND
dc.titleSynthesis and pre-clinical evaluation of a [F-18] fluoromethyl-tanaproget derivative for imaging of progesterone receptor expression
dc.typeJournal Article
rioxxterms.versionofrecord10.1039/c6ra07404a
rioxxterms.licenseref.startdate2016-01-01
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfRSC ADVANCES
pubs.issue62
pubs.notesNo embargo
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/PET Radiochemistry
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/PET Radiochemistry
pubs.publication-statusPublished
pubs.volume6
pubs.embargo.termsNo embargo
icr.researchteamPET Radiochemistry
dc.contributor.icrauthorSmith, Graham


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