Synthesis and pre-clinical evaluation of a [F-18] fluoromethyl-tanaproget derivative for imaging of progesterone receptor expression
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Date
2016-01-01ICR Author
Author
Merchant, S
Allott, L
Carroll, L
Tittrea, V
Kealey, S
Witney, TH
Miller, PW
Smith, G
Aboagye, EO
Type
Journal Article
Metadata
Show full item recordAbstract
<p>This work features the synthesis and biological evaluation of a novel fluorinated derivative of tanaproget and a carbon-11 labelled analogue, a high affinity non-steroidal PR ligand, as a possible candidate for imaging PR expression<italic>in vivo</italic>.</p>
Collections
Subject
Science & Technology
Physical Sciences
Chemistry, Multidisciplinary
Chemistry
BREAST-CANCER
ENDOCRINE THERAPY
ESTROGEN
PET
CARCINOMA
AFFINITY
ANALOGS
LIGAND
Research team
PET Radiochemistry
Language
eng
License start date
2016-01-01
Citation
RSC ADVANCES, 2016, 6 (62), pp. S7569 - S7579 (11)
Publisher
ROYAL SOC CHEMISTRY