Love laughs at Locksmiths: Ubiquitylation of p62 unlocks its autophagy receptor potential.
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Date
2017-05-01Author
Conway, O
Kirkin, V
Type
Journal Article
Metadata
Show full item recordAbstract
The multimodular adapter p62/sequestosome-1 plays prominent roles in physiology and disease by mediating cell signaling and cargo degradation. The work by Peng et al. published recently in Cell Research provides mechanistic insights into activation of its autophagy receptor function critical for maintaining cell homeostasis during various forms of stress.
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Research team
Cell Death and Immunity
Cancer Pharmacology & Stress Response (CPSR)
Language
eng
Date accepted
2017-05-01
License start date
2017-05
Citation
Cell research, 2017, 27 (5), pp. 595 - 597
Publisher
INST BIOCHEMISTRY & CELL BIOLOGY