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Love laughs at Locksmiths: Ubiquitylation of p62 unlocks its autophagy receptor potential.

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Publication Date
2017-05
ICR Author
Kirkin, Vladimir
Conway, Owen
Author
Conway, O
Kirkin, V
Type
Journal Article
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Abstract
The multimodular adapter p62/sequestosome-1 plays prominent roles in physiology and disease by mediating cell signaling and cargo degradation. The work by Peng et al. published recently in Cell Research provides mechanistic insights into activation of its autophagy receptor function critical for maintaining cell homeostasis during various forms of stress.
URL
https://repository.icr.ac.uk/handle/internal/733
Collections
  • Breast Cancer Research
  • Cancer Therapeutics
Licenseref URL
http://www.rioxx.net/licenses/all-rights-reserved
Version of record
10.1038/cr.2017.56
Research team
Cell Death and Immunity
Cancer Pharmacology & Stress Response (CPSR)
Language
eng
Date accepted
2017-05-01
License start date
2017-05
Citation
Cell research, 2017, 27 (5), pp. 595 - 597

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