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High-dimensional functional phenotyping of preclinical human CAR T cells using mass cytometry.
Here, we present a comprehensive protocol for the generation and functional characterization of chimeric antigen receptor (CAR) T cells and their products by mass cytometry in a reproducible and scalable manner. We describe ...
The Heterocellular Emergence of Colorectal Cancer.
(2017-02)
Tissues contain multiple different cell types and can be considered to be heterocellular systems. Signaling between different cells allows tissues to achieve phenotypes that no cell type can achieve in isolation. Such ...