Browsing Other ICR Research by title
Now showing items 126-145 of 1079
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B-cell lymphomas with discordance between pathological features and clinical behavior
(Springer Science and Business Media LLC, 2017-10) -
Bacterial genotypic and patient risk factors for adverse outcomes in Escherichia coli bloodstream infections: a prospective molecular epidemiological study.
(Oxford University Press (OUP), 2022-05-29)OBJECTIVES: Escherichia coli bloodstream infections have shown a sustained increase in England, for reasons that are unknown. Furthermore, the contribution of MDR lineages such as ST131 to overall E. coli disease burden ... -
Bayesian disclosure risk assessment: predicting small frequencies in contingency tables
(2007-11)We propose an approach for assessing the risk of individual identification in the release of categorical data. This requires the accurate calculation of predictive probabilities for those cells in a contingency table which ... -
Benign biliary diseases
(Elsevier BV, 2017-08) -
Best practice in active surveillance for men with prostate cancer: a Prostate Cancer UK consensus statement.
(2019-07)OBJECTIVES:To develop a consensus statement on current best practice of active surveillance (AS) in the UK, informed by patients and clinical experts. SUBJECTS AND METHODS:A consensus statement was drafted on the basis of ... -
beta-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells
(CELL PRESS, 2010-12-14)Identification of molecular pathways essential for cancer stem cells is critical for understanding the underlying biology and designing effective cancer therapeutics. Here, we demonstrated that beta-catenin was activated ... -
Between-region genetic divergence reflects the mode and tempo of tumor evolution.
(2017-07)Given the implications of tumor dynamics for precision medicine, there is a need to systematically characterize the mode of evolution across diverse solid tumor types. In particular, methods to infer the role of natural ... -
Bilateral mammoplasty for cancer: Surgical, oncological and patient-reported outcomes.
(2017-01)Introduction Bilateral mammoplasty (BM) can optimise oncological safety and aesthetic outcomes in women with large or ptotic breasts whose tumour to breast volume ratio or tumour location pose a challenge to standard ... -
Biochemical identification of a neutral sphingomyelinase 1 (NSM1)-like enzyme as the major NSM activity in the DT40 B-cell line: absence of a role in the apoptotic response to endoplasmic reticulum stress
(2002-07-01)DT40 cells have approx. 10-fold higher Mg2+-dependent neutral sphingomyelinase (NSM) activity in comparison with other B-cell lines and contain very low acidic sphingomyelinase activity, Purification of this activity from ... -
Biomarker analyses in REGARD gastric/GEJ carcinoma patients treated with VEGFR2-targeted antibody ramucirumab.
(2016-10)Background Angiogenesis inhibition is an important strategy for cancer treatment. Ramucirumab, a human IgG1 monoclonal antibody that targets VEGF receptor 2 (VEGFR2), inhibits VEGF-A, -C, -D binding and endothelial cell ... -
BMJ Open Qualitylaunch
(BMJ, 2017-07) -
Body fatness and physical activity at young ages and the risk of breast cancer in premenopausal women
(NATURE PUBLISHING GROUP, 2005-10-03)We examined the relationship between body fatness, sports participation and breast cancer risk in 1560 premenopausal cases and 1548 controls, from three related population-based case - control studies in the UK. Half of ... -
Breaking Bad News Training in the COVID-19 Era and Beyond.
(2020-01)COVID-19 has disrupted the status quo for healthcare education. As a result, redeployed doctors and nurses are caring for patients at the end of their lives and breaking bad news with little experience or training. This ... -
Breast cancer onset in twins and women with bilateral disease
(AMER SOC CLINICAL ONCOLOGY, 2008-09-01)Purpose Little is known of the onset of breast cancer in high- risk populations. We investigated the risk of breast cancer in twin sisters and in the contralateral breast taking family history into consideration. Patients ... -
Breast cancer survivorship: key issues and priorities of care
(Royal College of General Practitioners, 2017-03) -
Breast cancer susceptibility - A new look at an old model
(2002-06)A polygenic model in which many individually weak genes combine multiplicately to cause a 50-fold range of risk in the population explains several puzzling aspects of familial breast cancer epidemiology, including the very ...
