Browsing Other ICR Research by title
Now showing items 280-299 of 1001
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Early growth response 2 regulates the survival of thymocytes during positive selection
(WILEY-V C H VERLAG GMBH, 2010-01)The early growth response (Egr) transcription factor family regulates multiple steps during T-cell development. We examine here the role played by Egr2 in positive selection. in double-positive cells, Egr2 is upregulated ... -
ED11.01 Systemic Therapy for Advanced Oncogene-Driven NSCLC
(Elsevier BV, 2017-01) -
Editorial
(Ovid Technologies (Wolters Kluwer Health), 2017-06) -
Effect of Age on the Efficacy and Safety of Lenvatinib in Radioiodine-Refractory Differentiated Thyroid Cancer in the Phase III SELECT Trial.
(2017-08)Purpose In the Study of (E7080) Lenvatinib in Differentiated Cancer of the Thyroid (SELECT), lenvatinib significantly prolonged progression-free survival (PFS) versus placebo in patients with radioiodine-refractory ... -
Effect of bariatric surgery on long-term cardiovascular outcomes: a nationwide nested cohort study.
AIMS :This study aims to evaluate the long-term effect of bariatric surgery on cardiovascular outcomes of patients with obesity. METHODS AND RESULTS :A nested cohort study was carried out within the Clinical Practice ... -
Effect of manipulation of primary tumour vascularity on metastases in an adenocarcinoma model
(2002-01-07)One explanation for the clinical association between tumour vascularity and probability of metastasis is that increased primary tumour vascularity enhances haematogenous dissemination by offering greater opportunity for ... -
Effect of radium-223 dichloride (Ra-223) on hospitalisation: An analysis from the phase 3 randomised Alpharadin in Symptomatic Prostate Cancer Patients (ALSYMPCA) trial.
(2017-01)Symptomatic skeletal events (SSEs) commonly occur in patients with bone metastases, often leading to hospitalisations and decreased quality-of-life. In the ALSYMPCA trial, radium-223 significantly improved overall survival ... -
Effectiveness of contrast-associated acute kidney injury prevention methods; a systematic review and network meta-analysis.
(2018-11-13)Background Different methods to prevent contrast-associated acute kidney injury (CA-AKI) have been proposed in recent years. We performed a mixed treatment comparison to evaluate and rank suggested interventions.Methods A ... -
Effects of stray light on the fidelity of photodirected oligonucleotide array synthesis
(2002-10-01)Fabrication of high density oligonucleotide arrays using metal on glass photolithographic masks is inflexible and expensive. Maskless methods using computer-controlled projection have been proposed and implemented, but ... -
Efficacy and Safety of Radium-223 Dichloride in Symptomatic Castration-resistant Prostate Cancer Patients With or Without Baseline Opioid Use From the Phase 3 ALSYMPCA Trial.
(2016-11)Background The phase 3 ALSYMPCA trial enrolled metastatic castration-resistant prostate cancer patients with or without baseline opioid use.Objective To assess the efficacy and safety of radium-223 dichloride (radium-223) ... -
Efficacy of adjuvant chemotherapy with carboplatin for early triple negative breast cancer: a single center experience
(Impact Journals, LLC, 2017-09-26) -
ELM-the eukaryotic linear motif resource in 2020.
(2020-01)The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). Since the initial release almost 20 years ago, ELM has become an indispensable resource ... -
ELM: the status of the 2010 eukaryotic linear motif resource.
(2010-01)Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes through protein modifications at linear motifs. ... -
Embryonal Rhabdomyosarcoma of the Ovary and Fallopian Tube: Rare Neoplasms Associated With Germline and Somatic DICER1 Mutations.
(2020-06)DICER1 mutations (somatic or germline) are associated with a variety of uncommon neoplasms including cervical and genitourinary embryonal rhabdomyosarcoma (ERMS). We report a primary ovarian and 2 primary fallopian tube ... -
Emerging Novel Therapeutic Agents in the Treatment of Patients with Gastroesophageal and Gastric Adenocarcinoma.
(2017-06)With further understanding of the biology of gastric and gastroesophageal adenocarcinomas, strides are being made to find effective treatments through novel trial designs. This article focuses on the ongoing trials of drugs ... -
End-of-life care for homeless people: A qualitative analysis exploring the challenges to access and provision of palliative care
(SAGE Publications, 2018-01)<jats:sec><jats:title>Background:</jats:title><jats:p> Being homeless or vulnerably housed is associated with death at a young age, frequently related to medical problems complicated by drug or alcohol dependence. Homeless ... -
Endoscopic submucosal dissection: an update on tools and accessories.
(2020-01)Endoscopic submucosal dissection (ESD) is a minimally invasive therapeutic procedure to remove larger polyps or early non-metastatic lesions. It has long been used in Asia, but is now fast growing in popularity in the West. ...
