ELM-the eukaryotic linear motif resource in 2020.
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Date
2020-01-08ICR Author
Author
Kumar, M
Gouw, M
Michael, S
Sámano-Sánchez, H
Pancsa, R
Glavina, J
Diakogianni, A
Valverde, JA
Bukirova, D
Čalyševa, J
Palopoli, N
Davey, NE
Chemes, LB
Gibson, TJ
Type
Journal Article
Metadata
Show full item recordAbstract
The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). Since the initial release almost 20 years ago, ELM has become an indispensable resource for the molecular biology community for investigating functional regions in many proteins. In this update, we have added 21 novel motif classes, made major revisions to 12 motif classes and added >400 new instances mostly focused on DNA damage, the cytoskeleton, SH2-binding phosphotyrosine motifs and motif mimicry by pathogenic bacterial effector proteins. The current release of the ELM database contains 289 motif classes and 3523 individual protein motif instances manually curated from 3467 scientific publications. ELM is available at: http://elm.eu.org.
Collections
Subject
Cytoskeleton
DNA Damage
Phosphotyrosine
Amino Acid Motifs
src Homology Domains
Databases, Protein
Eukaryota
Apicoplasts
Language
eng
Date accepted
2019-10-23
License start date
2020-01
Citation
Nucleic acids research, 2020, 48 (D1), pp. D296 - D306
Publisher
OXFORD UNIV PRESS