Publications Repository

Publications Repository

View Item 
  •   Home
  • ICR Divisions
  • Closed Research Teams
  • View Item
  • Home
  • ICR Divisions
  • Closed Research Teams
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Randomised controlled trial of mammographic screening in women from age 40: results of screening in the first 10 years

Thumbnail
View/Open
Published version (97.88Kb)
Publication Date
2005-03-14
ICR Author
Moss, Susan Mary
Author
Moss, S
Thomas, I
Evans, A
Thomas, B
Johns, L
Grp, TM
Type
Journal Article
Metadata
Show full item record
Abstract
Debate continues over the effectiveness of screening by mammography in women below age 50. We report here on results of screening in the first 10 years of a randomised trial to study the effect on breast cancer mortality of invitation to annual mammography from age 40 to 41 compared to first invitation to the 3-yearly UK national programme at age 50-52. The trial is taking place in 23 NHS breast screening centres. Between 1991 and 1997, 160 921 women were randomised in the ratio 1 : 2 to intervention and control arms. Screening is by two views at first screen and single view subsequently; data on screening up to and including round five are now complete. Uptake of invitation to screening is between 68 and 70% at all but the latest screening rounds. Rates of referral for assessment are 4.6% at first screen and 3.4% at subsequent screens. Invasive cancer detection rates are 0.09% at first screen, and similar at rescreens until the sixth and later screens. There is little evidence of regular mammography in the trial control arm. The setting of this trial within the NHS breast screening programme should ensure applicability of results to a national programme.
URL
https://repository.icr.ac.uk/handle/internal/2578
Collections
  • Closed Research Teams
Version of record
10.1038/sj.bjc.6602396
Research team
Cancer Screening Evaluation Unit (DoH)
Language
English
License start date
2005-03-14
Citation
BRITISH JOURNAL OF CANCER, 2005, 92 pp. 949 - 954
Publisher
NATURE PUBLISHING GROUP

Browse

All of ICR repositoryICR DivisionsIssue dateAuthorsTitlesSubjectsThis collectionIssue dateAuthorsTitlesSubjects

Statistics

Most popular itemsStatistics by countryMost popular authors
  • Login
  • Registered office: The Institute of Cancer Research, 123 Old Brompton Road, London, SW7 3RP
    A Charity, Not for Profit. Company Limited by Guarantee.
    Registered in England No. 534147. VAT Registration No. GB 849 0581 02.