Short tandem repeat profiling provides an international reference standard for human cell lines
dc.contributor.author | Masters, JR | |
dc.contributor.author | Thomson, JA | |
dc.contributor.author | Daly-Burns, B | |
dc.contributor.author | Reid, YA | |
dc.contributor.author | Dirks, WG | |
dc.contributor.author | Packer, P | |
dc.contributor.author | Toji, LH | |
dc.contributor.author | Ohno, T | |
dc.contributor.author | Tanabe, H | |
dc.contributor.author | Arlett, CF | |
dc.contributor.author | Kelland, LR | |
dc.contributor.author | Harrison, M | |
dc.contributor.author | Virmani, A | |
dc.contributor.author | Ward, TH | |
dc.contributor.author | Ayres, KL | |
dc.contributor.author | Debenham, PG | |
dc.date.accessioned | 2018-09-26T08:14:49Z | |
dc.date.issued | 2001-07-03 | |
dc.identifier | 14 | |
dc.identifier.citation | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 pp. 8012 - 8017 | |
dc.identifier.issn | 0027-8424 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/2865 | |
dc.identifier.doi | 10.1073/pnas.121616198 | |
dc.description.abstract | Cross-contamination between cell lines is a longstanding and frequent cause of scientific misrepresentation. Estimates from national testing services indicate that up to 36% of cell lines are of a different origin or species to that claimed. To test a standard method of cell line authentication, 253 human cell lines from banks and research institutes worldwide were analyzed by short: tandem repeat profiling. The short tandem repeat profile is a simple numerical code that is reproducible between laboratories, is inexpensive, and can provide an international reference standard for every cell line. If DMA profiling of cell lines is accepted and demanded internationally, scientific misrepresentation because of cross-contamination can be largely eliminated. | |
dc.format.extent | 8012 - 8017 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | NATL ACAD SCIENCES | |
dc.rights.uri | https://www.rioxx.net/licenses/all-rights-reserved | |
dc.title | Short tandem repeat profiling provides an international reference standard for human cell lines | |
dc.type | Journal Article | |
rioxxterms.versionofrecord | 10.1073/pnas.121616198 | |
rioxxterms.licenseref.uri | https://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.licenseref.startdate | 2001-07-03 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | |
pubs.notes | affiliation: Masters, JR (Reprint Author), UCL, Inst Urol, 3rd Floor Res Labs,67 Riding House St, London W1W 7EY, England. UCL, Inst Urol, London W1W 7EY, England. Lab Govt Chemist, Teddington TW11 0LY, Middx, England. Amer Type Culture Collect, Manassas, VA 20110 USA. Deutsch Sammlung Mikroorganism Zellkultur GmbH, German Collect Cell Cultures, D-38124 Braunschweig, Germany. European Collect Anim Cell Cultures, Ctr Appl Microbiol & Res, Salisbury SP4 0JG, Wilts, England. Coriell Inst Med Res, Camden, NJ 08103 USA. RIKEN, Inst Phys & Chem Res, Cell Bank, Tsukuba, Ibaraki 3050074, Japan. Natl Inst Hlth Sci, Collect Res Bioresources Cell Bank, Tokyo 1588501, Japan. Univ Sussex, MRC, Cell Mutat Unit, Brighton BN1 9RR, E Sussex, England. Inst Canc Res, CRC, Ctr Canc Therapeut, Sutton SM2 5NG, Surrey, England. Univ Texas, SW Med Ctr, Hamon Ctr Therapeut Oncol Res, Dallas, TX 75235 USA. Imperial Canc Res Fund, London WC2A 3PX, England. Paterson Inst Canc Res, Dept Drug Dev, Manchester M20 4BX, Lancs, England. Univ Reading, Dept Appl Stat, Reading RG6 6FN, Berks, England. keywords-plus: CROSS-CONTAMINATION; DNA; IDENTIFICATION; CULTURES; SYSTEM; INDIVIDUALIZATION; AUTHENTICATION; FINGERPRINTS; ISOENZYME; HELA research-areas: Science & Technology - Other Topics web-of-science-categories: Multidisciplinary Sciences author-email: [email protected] researcherid-numbers: Masters, John/C-5694-2011 number-of-cited-references: 30 times-cited: 268 usage-count-last-180-days: 1 usage-count-since-2013: 12 journal-iso: Proc. Natl. Acad. Sci. U. S. A. doc-delivery-number: 450LK unique-id: ISI:000169744200067 oa: gold_or_bronze da: 2018-09-24 | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR | |
pubs.volume | 98 | |
pubs.embargo.terms | Not known | |
dc.contributor.icrauthor | Kelland, Lloyd | en |