| dc.contributor.author | Williams, MJ | |
| dc.contributor.author | Werner, B | |
| dc.contributor.author | Graham, TA | |
| dc.contributor.author | Sottoriva, A | |
| dc.date.accessioned | 2017-03-01T12:26:09Z | |
| dc.date.issued | 2016-07 | |
| dc.identifier.citation | Molecular & cellular oncology, 2016, 3 (4), pp. e1162897 - ? | |
| dc.identifier.issn | 2372-3556 | |
| dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/443 | |
| dc.identifier.eissn | 2372-3556 | |
| dc.identifier.doi | 10.1080/23723556.2016.1162897 | |
| dc.description.abstract | Next-generation sequencing data from human cancers are often difficult to interpret within the context of tumor evolution. We developed a mathematical model describing the accumulation of mutations under neutral evolutionary dynamics and showed that 323/904 cancers (∼30%) from multiple types were consistent with the neutral model of tumor evolution. | |
| dc.format | Electronic-eCollection | |
| dc.format.extent | e1162897 - ? | |
| dc.language | eng | |
| dc.language.iso | eng | |
| dc.title | Functional versus non-functional intratumor heterogeneity in cancer. | |
| dc.type | Journal Article | |
| dcterms.dateAccepted | 2016-03-02 | |
| rioxxterms.versionofrecord | 10.1080/23723556.2016.1162897 | |
| rioxxterms.licenseref.startdate | 2016-07 | |
| rioxxterms.type | Journal Article/Review | |
| dc.relation.isPartOf | Molecular & cellular oncology | |
| pubs.issue | 4 | |
| pubs.notes | Not known | |
| pubs.organisational-group | /ICR | |
| pubs.organisational-group | /ICR | |
| pubs.publication-status | Published | |
| pubs.volume | 3 | |
| pubs.embargo.terms | Not known | |
| dc.contributor.icrauthor | Sottoriva, Andrea | en |
