MR-guided radiotherapy for prostate cancer: state of the art and future perspectives.
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Date
2022-03-01ICR Author
Author
Sritharan, K
Tree, A
Type
Journal Article
Metadata
Show full item recordAbstract
Advances in radiotherapy technology have increased precision of treatment delivery and in some tumour types, improved cure rates and decreased side effects. A new generation of radiotherapy machines, hybrids of an MRI scanner and a linear accelerator, has the potential to further transform the practice of radiation therapy in some cancers. Facilitating superior image quality and the ability to change the dose distribution online on a daily basis (termed "daily adaptive replanning"), MRI-guided radiotherapy machines allow for new possibilities including increasing dose, for hard to treat cancers, and more selective sparing of healthy tissues, where toxicity reduction is the key priority.These machines have already been used to treat most types of cancer, although experience is still in its infancy. This review summarises the potential and current evidence for MRI-guided radiotherapy, with a predominant focus on prostate cancer. Current advantages and disadvantages are discussed including a realistic appraisal of the likely potential to improve patient outcomes. In addition, horizon scanning for near-term possibilities for research and development will hopefully delineate the potential role for this technology over the next decade.
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Subject
Humans
Prostatic Neoplasms
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Radiation Oncology
Particle Accelerators
Male
Magnetic Resonance Imaging, Interventional
Radiotherapy, Image-Guided
Language
eng
License start date
2022-03
Citation
The British journal of radiology, 2022, 95 (1131), pp. 20210800 - ?
Publisher
BRITISH INST RADIOLOGY