Magnetic Resonance Spectroscopy (MRS)-Based Methods for Examining Cancer Metabolism in Response to Oncogenic Kinase Drug Treatment.
MetadataShow full item record
Magnetic resonance spectroscopy (MRS) is an analytical technique that has been extensively used to examine reprogrammed metabolism and treatment response in cancer cells and solid tumors both in vivo and ex vivo. High-resolution MRS (HR-MRS) is one of the best methods for metabolic profiling, as it is highly quantitative, robust, and reproducible. The protocols for dual-phase extraction of cancer cells and tumors and sample preparations for high-resolution (1)H and (31)P HR-MRS analysis are described here. Descriptions of spectra acquisition and analysis are also included in this chapter.
Version of record
Magnetic resonance spectroscopy
Nuclear magnetic resonance spectroscopy
License start date
Methods Mol Biol, 2017, 1636 pp. 393 - 404