dc.contributor.author | Di Micco, R | |
dc.contributor.author | O'Connell, RL | |
dc.contributor.author | Barry, PA | |
dc.contributor.author | Roche, N | |
dc.contributor.author | MacNeill, FA | |
dc.contributor.author | Rusby, JE | |
dc.date.accessioned | 2017-04-21T16:25:10Z | |
dc.date.issued | 2017-01 | |
dc.identifier.citation | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2017, 43 (1), pp. 68 - 75 | |
dc.identifier.issn | 0748-7983 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/610 | |
dc.identifier.eissn | 1532-2157 | |
dc.identifier.doi | 10.1016/j.ejso.2016.08.013 | |
dc.description.abstract | Introduction Bilateral mammoplasty (BM) can optimise oncological safety and aesthetic outcomes in women with large or ptotic breasts whose tumour to breast volume ratio or tumour location pose a challenge to standard breast-conserving therapy (BCT) and for whom mastectomy (with or without reconstruction) may be the only alternative.Methods We undertook a comprehensive analysis of surgical outcomes (complications according to the Clavien Dindo classification), acute radiation morbidity (Radiation Therapy Oncology Group classification), oncological outcomes, and patient satisfaction (BREAST-Q questionnaire) in women who underwent BM for breast cancer (BC) from June 2009-November 2014.Results 168 women were included. Median age was 55 years (range:33-84) and median tumour size at imaging 35 mm (range:0-170). Median specimen weight was 242 g (range 39-1824). The wise pattern technique was used in 87.5% of procedures. At least one complication occurred in 68 (40.5%) women, mostly Clavien Dindo grade 1. Grade 3 complications were infrequent (8.9%) but occurred mainly on the therapeutic mammoplasty (TM) side (p < 0.05). Complications were associated with higher BMI, specimen weight and longer time to radiotherapy (p < 0.05). Median follow-up was 37 months (range: 13-77). Local recurrence occurred in 3 (1.8%), distant metastases in 5 (3.0%), and 10 (6.0%) women have died. The median score for 'satisfaction with breasts' was 77 (range: 0-100).Conclusions This study provides concurrent data on surgical, oncological and patient-reported outcomes. It offers evidence that BM is an effective treatment for breast cancer in large- or ptotic-breasted women. | |
dc.format | Print-Electronic | |
dc.format.extent | 68 - 75 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.rights.uri | https://www.rioxx.net/licenses/all-rights-reserved | |
dc.subject | Humans | |
dc.subject | Breast Neoplasms | |
dc.subject | Postoperative Complications | |
dc.subject | Treatment Outcome | |
dc.subject | Mammaplasty | |
dc.subject | Follow-Up Studies | |
dc.subject | Esthetics | |
dc.subject | Adult | |
dc.subject | Aged | |
dc.subject | Aged, 80 and over | |
dc.subject | Middle Aged | |
dc.subject | Patient Satisfaction | |
dc.subject | Female | |
dc.subject | Surveys and Questionnaires | |
dc.title | Bilateral mammoplasty for cancer: Surgical, oncological and patient-reported outcomes. | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2016-08-10 | |
rioxxterms.versionofrecord | 10.1016/j.ejso.2016.08.013 | |
rioxxterms.licenseref.uri | https://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.licenseref.startdate | 2017-01 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology | |
pubs.issue | 1 | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/Royal Marsden Clinical Units | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/Royal Marsden Clinical Units | |
pubs.publication-status | Published | |
pubs.volume | 43 | |
pubs.embargo.terms | Not known | |
dc.contributor.icrauthor | Rusby, Jennifer | |
dc.contributor.icrauthor | Marsden, | |