Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine
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Date
2014ICR Author
Author
Hiley, C
de Bruin, EC
McGranahan, N
Swanton, C
Type
Other
Metadata
Show full item recordAbstract
The presence of multiple subclones within tumors mandates understanding of longitudinal and spatial subclonal dynamics. Resolving the spatial and temporal heterogeneity of subclones with cancer driver events may offer insight into therapy response, tumor evolutionary histories and clinical trial design.
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https://genomebiology.biomedcentral.com/track/pdf/10.1186/s13059-014-0453-8Collections
Language
eng
License start date
2014
Citation
GENOME BIOLOGY, 2014, 15
Publisher
BIOMED CENTRAL LTD