Recent submissions
Now showing items 321-340 of 622
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Marker-less online MR-guided stereotactic body radiotherapy of liver metastases at a 1.5 T MR-Linac - Feasibility, workflow data and patient acceptance.
Introduction Stereotactic body radiotherapy (SBRT) is an established ablative treatment for liver tumors with excellent local control rates. Magnetic resonance imaging guided radiotherapy (MRgRT) provides superior soft ... -
Can self-management programmes change healthcare utilisation in COPD?: A systematic review and framework analysis.
Objective The study aims to evaluate the ability of self-management programmes to change the healthcare-seeking behaviours of people with Chronic Obstructive Pulmonary Disease (COPD), and any associations between programme ... -
Development of an online research platform for use in a large-scale multicentre study.
Background Participation in research can be beneficial for patients and healthcare providers, but may prove demanding at patient, clinician and organizational levels. Patient representatives are supportive of online research ... -
Head and neck mucosal melanoma: The United Kingdom national guidelines.
(ELSEVIER SCI LTD, 2020-10-01)The United Kingdom head and neck mucosal melanoma guideline development group used an evidence-based systematic approach to make recommendations in key areas of uncertainty in the field, including accurate diagnosis and ... -
Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System
(Elsevier BV, 2017-10-01) -
The risk-value trade-off: price and brand information impact consumers' intentions to purchase OTC drugs.
(2021-01-25)<h4>Background</h4>European countries face fiscal pressure regarding the long-term sustainability of their healthcare system due to increasing levels of public health expenditures and mounting demographic pressures. The ... -
DisProt: intrinsic protein disorder annotation in 2020.
(OXFORD UNIV PRESS, 2020-01-08)The Database of Protein Disorder (DisProt, URL: https://disprot.org) provides manually curated annotations of intrinsically disordered proteins from the literature. Here we report recent developments with DisProt (version ... -
Are disruptive innovations recognised in the healthcare literature? A systematic review.
The study aims to conduct a systematic review to characterise the spread and use of the concept of 'disruptive innovation' within the healthcare sector. We aim to categorise references to the concept over time, across ... -
Nivolumab Plus Ipilimumab for Treatment-Naïve Metastatic Uveal Melanoma: An Open-Label, Multicenter, Phase II Trial by the Spanish Multidisciplinary Melanoma Group (GEM-1402).
(2021-01-08)Purpose This study aimed to assess the efficacy of the combination of nivolumab (nivo) plus ipilimumab (ipi) as a first-line therapy with respect to the 12-month overall survival (OS) in patients with metastatic uveal ... -
Fiducial marker based intra-fraction motion assessment on cine-MR for MR-linac treatment of prostate cancer.
(2019-04-04)We have developed a method to determine intrafraction motion of the prostate through automatic fiducial marker (FM) tracking on 3D cine-magnetic resonance (MR) images with high spatial and temporal resolution. Twenty-nine ... -
National survey of fiducial marker insertion for prostate image guided radiotherapy.
(ELSEVIER SCI LTD, 2018-11-01)INTRODUCTION: In the United Kingdom fiducial marker IGRT is the second most common verification method employed in radical prostate radiotherapy yet little evidence exists to support centres introducing or developing this ... -
The Emerging Role of Local Therapy in Metastatic Prostate Cancer.
(2020-01-20)PURPOSE OF REVIEW:This review summarizes the prospective clinical evidence regarding local therapy in metastatic prostate cancer. RECENT FINDINGS:The phase 3 STAMPEDE trial showed that prostate radiotherapy confers a ... -
Toward Point-of-care Uropathogen Detection Using SERS Active Filters
(SPIE-INT SOC OPTICAL ENGINEERING, 2020-01-01) -
Simulation of Patient-Specific Deformable Ultrasound Imaging in Real Time
(SPRINGER INTERNATIONAL PUBLISHING AG, 2017-01-01) -
Intuitive Gaze-Control of a Robotized Flexible Endoscope
(IEEE, 2018-01-01) -
Optimizing the Timing of Salvage Postprostatectomy Radiotherapy and the Use of Concurrent Hormonal Therapy for Prostate Cancer.
(2018-05-15)Context Currently, salvage radiotherapy (SRT) is the only known curative intervention for men with recurrent disease following prostatectomy. Critical issues in the optimal selection and management of men being considered ... -
What Type of Prostate Cancer Is Systematically Overlooked by Multiparametric Magnetic Resonance Imaging? An Analysis from the PROMIS Cohort.
Background All risk stratification strategies in cancer overlook a spectrum of disease. The Prostate MR Imaging Study (PROMIS) provides a unique opportunity to explore cancers that are overlooked by multiparametric magnetic ... -
Prostate radiotherapy in newly diagnosed metastatic prostate cancer.
Purpose of review The aim of this article is to review the role of prostate radiotherapy in the multimodal management of newly diagnosed metastatic hormone naïve prostate cancer.Recent findings Two randomized controlled ...